As part of a court settlement being negotiated with US, wealthy family would give up control of drugmaker accused of fueling opioid crisis

Tentative agreement reached with thousands of local governments and more than 20 states, could be worth up to $12 billion over time

Sackler-owned company has threatened bankruptcy, which could complicate efforts by states and victims to get compensation

Family refuses to offer counter-proposal, expected to seek protection from courts as lawsuit against maker of addictive painkiller set to go ahead

Figures show Israeli pharmaceutical giant produced less than 1% of the 76 billion oxycodone and hydrocodone pills; Sackler-owned Purdue produced about 3% in 2006-2012

Jewish family, founder of Purdue Pharma and famous for philanthropy, has become notorious for causing mass-scale drug addiction. Will institutions reject their donations?

Drug company used Italian doctor, apparently employing practices that helped create US addiction crisis that has claimed 400,000 lives

Pennsylvania says Purdue Pharma, owned by the Sackler family, ignored signs drug was being over-prescribed